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diagnosis leukemia algorithm lymphocytic lymphoma management rheumatology workup agglutinin anemia causes classification cold comparison diffuse disease erythematosus hemeonc hemolytic lupus
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involvement Differential ... • Other hematologic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Age > 50 • Chronic ... Reed-Sternberg Cells ... Lymphadenopathy #LAD ... Algorithm #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... activity • ↓ LAP ... • Peripheral smear ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... identical to the non-Hodgkin ... • Peripheral smear ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
cells. ... accounts for 10% of all ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... • Peripheral smear ... #Leukemia #oncology ... #hematology #hemeonc
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Marrow Failure • Chronic ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
IgM) • Blood smear ... malignancies -> CLL ... younger pts) Differential ... sensitize red blood cells ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... with Lupus: • Chronic ... cyclophosphamide) • Hodgkin
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Too many cells in ... Better call hematology ... normal/high - Chronic ... hypoxia & bad oxygen
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