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differential management treatment hematology oncology opportunistic prevention nephrology clinical hematuria infectiousdiseases urine algorithm cardiology endocarditis mds myelodysplastic pulmonary renal syndromes
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• Red cell casts ... • White cell casts ... • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine • 1ml blood ... deposits - Post-infectious ... hematuria: - RBC casts ... Hematuria: • Infection ... #renal #urine #blood
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... Urinary tract infections ... 34t5DgJ #Urinary #Casts
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... • Peripheral blood ... Fevers, DAT (-) → Infection ... #Differential #Diagnosis ... #Algorithm #causes
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Algorithm Red blood ... cells on urine ... microscopy. ... RBCs and/or RBC casts ... glomerulonephritis • Post-Infectious
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... skin that are caused ... petechiae) • Frequent infections ... • Parvovirus infection ... Myelodysplastic #Syndromes #diagnosis
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS Preventing Bacterial Enteric Illness: • Antimicrobial
IDSA Recommendations ... Bacterial Enteric Infections ... • In rare cases ... Enteric #Bacterial #IDSA ... #HIVAIDS #pharmacology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... = funny-shaped cells ... old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks: infection
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... plateletcount), peripheral blood ... PLT in selected cases ... changes), high MCV anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... result from low blood ... oncology #hematology #diagnosis
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