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dermatology oncology management rheumatology smear leukemia skin chronic cll differential disease eschar hemolytic laboratory lymphocytic peripheral rash testing workup agglutinin
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... #Peripheral #Blood ... Smear #Analysis #hematology ... #microscopy #interpretation ... #clinical #anemia
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... and laboratory diagnosis ... #Hematology #Pathology ... #Smear #Microscopy
Some of the techniques used for Antenatal Diagnosis Amniocentesis - Chromosome/micro-array and DNA analysis -
— PCR Fetal blood ... haemoglobin for anaemia ... - Fetal infection ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... abnormal under a microscope ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Clinical Presentation ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... cells (RBCs) at ... #hematology #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Idiopathic • Infections ... result from low blood ... #oncology #hematology ... #diagnosis #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... of peripheral blood ... cultures, including blood ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... cells + production ... accumulation of clinical ... Assessment • Clinical ... treatment #summary #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... bacillus cause selsis ... possible Patient's clinical ... the key to the diagnosis ... #clinical #photo
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