40 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Peripheral #Blood ... #Smear #Analysis ... #hematology #microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
agglutinin disease and Infection ... Mycoplasma Pneumonia or Infectious ... individual’s red blood ... Clinical #Path #Blood ... #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
agglutinin disease and Infection ... Mycoplasma Pneumonia or Infectious ... individual’s red blood ... Clinical #Path #Blood ... #Smear #Microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... polychromatophilic cells ... hemolytic #anemia #Hematology ... #Microscopy
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Peripheral Smear ... → Refer to hematology ... : Acute blood loss ... #Differential #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... • Parvovirus infection ... smear • Bone marrow ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential Diagnosis ... • Peripheral blood ... smear + DAT + further ... Fevers, DAT (-) → Infection ... #Differential #Diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Internal (RBC) - Infections ... - Peripheral Blood ... Smear ↑ abnormal ... #hematology
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... from maternal blood
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... cells (RBCs) at ... hemolytic #anemia #hematology