17 results
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... signs/symptoms of active ... pulmonary TB PE ... of AFB by smear microscopy
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... likely it will be clinically ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... , Interstitial Pulmonary
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... Chronic kidney disease ... Langerhans giant cells ... characteristic features Clinical ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... Chronic kidney disease ... Langerhans giant cells ... characteristic features Clinical ... TB #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... : • 10%-15% Pulmonary ... Nephrogenic DI Hematologic ... muscarinic agonists • Active ... Diagnosis #Management
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... : • Clinical triad ... • Autoimmune diseases ... rheumatoid factor activity ... vasculitis - GPA, EGPA, microscopic
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... cirrhosis • Intra-pulmonary ... hepatopulmonary #syndrome ... #treatment #hepatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Multinucleated giant cells ... Mucocutaneous lymph node syndrome ... (PR3-ANCA)): Microscopic ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... , breast bone, pelvis ... osteoarticular and skin disease ... diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... absent NK cell activity ... #treatment #hematology