9 results
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... polychromatophilic cells ... hemolytic #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Normal Blood Smear ... B12 - Anti-IF Antibodies ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
(Diffuse) Anti-Sm ... Microscopic polyangiitis ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Anti-Sm (Smith) ... cases • Sjögren syndrome ... Vasculitis: • Microscopic ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... abnormal under a microscope ... Peripheral blood smear ... hematopoietic stem ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... IgM) • Blood smear ... sensitize red blood cells ... hemolytic #anemia #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... • Peripheral smear ... Schistocytes, helmet cells ... HIT: Heparin-PF4 antibodies ... #Coagulation #diagnosis
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Syndrome: 3d of ... LBRF can be diagnosed ... and convalescent antibodies ... recurrentis #BloodSmear #microscopy ... #pathology #clinical