15 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... anemia Sickled red cells ... Bite cells: G6PD ... Analysis #hematology #microscopy ... interpretation #clinical
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
A peripheral-blood ... smear revealed ... 25% plasma cells ... Wright–Giemsa stain) #Clinical ... #NEJM
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
A normal peripheral ... blood smear indicates ... appearance of red blood cells ... #Clinical #Path ... #Microscopy #PeripheralBloodSmear
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear ... #Peripheral #Pathology ... #Microscopy #Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... polychromatophilic cells ... smear changes are ... #Microscopy
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Smear: • Dysplastic ... differential • Peripheral ... blood smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
acanthocytes (or spur cells ... Spur cells acquire ... echinocytes (or burr cells ... #NEJM #clinical ... #blood #smear
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... patient with McLeod Syndrome ... SpurCells #McLeod #Syndrome ... #Smear #Pathology ... #Microscopy #Clinical
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... hematopoietic stem cells ... including peripheral ... blood myeloid cells ... NEJM Review: https