19 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
A peripheral-blood ... smear revealed ... 25% plasma cells ... stain) #Clinical #HONC ... #NEJM
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... anemia Sickled red cells ... Bite cells: G6PD ... #hematology #microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
by blood cells ... blood cells, red ... blood cells or ... cells - red blood ... cells, white blood
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... non-specific red cell ... polychromatophilic cells ... hemolytic #anemia #Hematology ... #Microscopy
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear ... Peripheral #Pathology #Microscopy ... #Clinical #Blood
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Skin: - CLL cells ... • Peripheral smear ... : Smudge cells or ... basket cells can
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy • Blast cells ... Rapidly rising blast cells ... : Granulocytic cells ... Cells are in the ... #Leukemia #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
adsorption onto cancer ... cells (and subsequent ... disorders • Shear ... Diagnosis #Management #treatment ... #hematology #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... glucocorticoid treatment ... Differential #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... Smear • Drugs ... Macrocytosis, Target Cells ... #Hematology