22 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... Sickled red cells ... Bite cells: G6PD ... #hematology #microscopy
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
A peripheral-blood ... smear revealed ... 25% plasma cells ... stain) #Clinical #HONC ... #NEJM
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... non-specific red cell ... polychromatophilic cells ... #Hematology #Pathology ... #Smear #Microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cells, red ... blood cells or ... cells - red blood ... cells, white blood ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... transfusion • Target cells ... • Sickle cells ... alcoholism • Burr cells ... #differential #hematology
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
Spur-Cell Anemia ... acanthocytes (or spur cells ... Spur cells acquire ... echinocytes (or burr cells ... #NEJM #clinical
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Smear • Drugs ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Skin: - CLL cells ... • Peripheral smear ... : Smudge cells or ... basket cells can