53 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Leukemia - Physical ... A peripheral-blood ... revealed 25% plasma cells ... stain) #Clinical #HONC ... #Smear #NEJM
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear #Peripheral ... #Pathology #Microscopy ... #Clinical #Blood
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy • Blast cells ... Rapidly rising blast cells ... : Granulocytic cells ... organs When Cancer Cells ... Hypogammaglobulinemia, smudge cells
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... anemia Sickled red cells ... Bite cells: G6PD ... #Blood #Smear # ... Analysis #hematology #microscopy
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
applies to any cells ... lymphocytes (B cells ... , T cells, and natural ... killer cells). ... in blast cells
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Leukemia • Idiopathic ... blood cells, red ... blood cells or ... cells - red blood ... cells, white blood
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
A normal peripheral ... blood smear indicates ... appearance of red blood ... cells, with a zone ... Clinical #Path #Microscopy
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... cytometry • Peripheral ... smear: Smudge cells ... or basket cells ... Lymphocytosis: Absolute blood
The hematopoietic tree and the resulting leukemias and lymphomas 
The hematopoietic tree refers to the hierarchical
organization of blood ... into all types of blood ... cells. ... gives rise to red blood ... types of white blood
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
confusion...A peripheral-blood ... acanthocytes (or spur cells ... Spur cells acquire ... echinocytes (or burr cells ... #NEJM #clinical