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hematology oncology management chronic cll leukemia lymphocytic workup acidosis aplastic canimorsus capnocytophaga causes cutaneous differential elevation eschar gangrenosum hemeonc hodgkins
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can infiltrate ... smear: Smudge cells ... or basket cells ... • Neutropenia, anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... immunophenotype Clinical ... 5) Symptoms of anemia ... #hemeonc #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... cellularity + dysplastic cells ... number of CD34+ cells ... Number of CD34+ cells
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Reed-Sternberg cells ... Hodgkin Lymphoma - Clinical ... • The tumor cells ... Hodgkin Lymphoma Treatment
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... bacillus cause selsis ... the key to the diagnosis ... #dermatology #clinical ... #photo
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
. diagnosis? ... No treatment is ... larva #migrans #skinRash ... #dermatology #clinical ... #photo
Rickettsialpox Eschar 40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis? Rickettsialpox R akari classic
Diagnosis? ... not endothelial cells ... Eschar #rakari #clinical ... #photo #skinrash ... #dermatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... perfusion - shock->treatments ... before beginning treatment ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
arises from plasma cells ... from the plasma cells ... plasmacytoma) Clinical ... monoclonal plasma cells ... clonal plasma cells
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Diagnosis? ... wide variety of clinical ... neutrophils & T-cells ... PG secondary treatment ... #photo #dermatology
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