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diagnosis hematology clinical differential smear causes bloodsmear algorithm path oncology management microscopy hemolytic pathology systemic atlas chronic cll dermatology generalized
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... blood smear or ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... A peripheral-blood ... revealed 25% plasma cells ... Plasmacytomas #PlasmaCell #Leukemia ... #Smear #NEJM
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... differential • Peripheral
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Sickled red cells ... disease Bite cells ... EricsMedicalLectures/ #Peripheral ... #Blood #Smear #
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
confusion...A peripheral-blood ... Spur cells acquire ... resolve despite blood ... #NEJM #clinical ... #peripheral #blood
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... 🔬Tumor cells are ... Prolymphocytes #Smear #Peripheral ... Microscopy #Clinical #Blood
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... virus (EBV) • Leukemia ... ) Labs: • Peripheral ... result from low blood
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... • Richter’s Syndrome ... • Sezary syndrome
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
defined as white blood ... circulate freely in peripheral ... blood; The rest ... the margins of blood ... cell type in the peripheral
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... hematopoietic stem cells ... including peripheral ... blood myeloid cells ... NEJM Review: https
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