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diagnosis differential management beriberi bloodsmear causes classification clinical deficiency elevation gitelman hypokalemia korsakoff lactate lactic manifestations nephrology nutrition rheumatology schistocytes
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #BloodSmear #Blood
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations Causes of Thiamine Deficiency: • Poor intake: - Diets
increase venous blood ... seen • Lactic acidosis ... vascular contraction, blood ... GFR • Acute liver ... beriberi #nutrition #pathophysiology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
removal from the blood ... e.g., uptake by cells ... glucose by the liver ... contribution of liver ... - Compartment syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... Pulmonary amyloidosis, PAH ... vasculitis: 10%-16% Liver ... renal tubular acidosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... apical membrane of cells ... Normal or low blood ... Renal tubular acidosis ... nephrology #management #pathophysiology
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