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diagnosis hematology clinical leukemia management radiology smear adenosine anemia antenatal aplastic autoinflammatory babesia babesiosis bloodsmear brucellasuis brucellosis cardiacstresstest chronic classification
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... cells, red blood ... cells - red blood ... cells, white blood ... diagnosis #hematology #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https
Some of the techniques used for Antenatal Diagnosis Amniocentesis - Chromosome/micro-array and DNA analysis -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... result from low blood ... Aplastic #Anemia #oncology
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... cells. ... In the right photo ... hemolytic- uremic syndromes ... Path #BloodSmear #Blood
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... Mediastinal mass) • CT ... marrow biopsy - if blood ... physical exam, CT ... classification #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - Blood and Bone ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
or basket cells ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology
Chronic Splenic Brucellosis - Computed tomography of the abdomen and pelvis revealed a coarsely calcified, circumscribed
the abdomen and pelvis ... Blood cultures were ... Clinical #Radiology #CT ... Brucellosis #Splenic #NEJM
Pemberton’s Sign in a Patient with a Goiter- Physical examination revealed an enlarged thyroid with no
superior vena cava syndrome ... #clinical #photo ... #NEJM #Pembertons ... sign #radiology #CT
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