10 results
Marfan’s Syndrome with Ectopia Lentis - Slit-lamp examination revealed ectopia lentis in both eyes, including near-complete
Marfan’s Syndrome ... with Ectopia Lentis ... revealed ectopia lentis ... #Clinical #Ophth ... LensDislocation #SlitLamp #NEJM
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... cells, red blood ... cells - red blood ... cells, white blood ... diagnosis #hematology #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... hematopoietic stem cells ... including peripheral blood ... myeloid cells ... NEJM Review: https
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
— PCR Fetal blood ... serology - Fetal blood ... genetic analysis of cells ... surgery, e.g. laser photo-coagulation ... transfusion syndrome
Acute Dacryocystitis- A 4-week-old boy was brought to the emergency department after having drainage from both
Cultures of urine, blood ... #NEJM #clinical ... #photo #peds #acute ... dacryocystitis #ophth
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... result from low blood ... Aplastic #Anemia #oncology
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... cells. ... In the right photo ... hemolytic- uremic syndromes ... Path #BloodSmear #Blood
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... - Blood and Bone ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
or basket cells ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology
Bitot's Spots- A 4-year-old boy was brought by his father to the ophthalmology clinic with a
photoreceptor cells ... #NEJM #clinical ... #photo #ophth #bitot