25 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... • Peripheral smear ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Peripheral smear ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... : Sickle cell disease ... #Smear #Analysis ... #hematology #microscopy
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... A peripheral-blood ... smear revealed ... 25% plasma cells ... #NEJM
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... blood cells or ... smear • Bone marrow ... #diagnosis #hematology ... #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
criteria for 1) hematologic ... (12%) • giant cell ... including peripheral blood ... myeloid cells ... NEJM Review: https
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
seen in the left photo ... are a teardrop cell ... In the right photo ... Path #BloodSmear #Blood ... #Smear #Helmet
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
photos show sickle ... blood smears. ... In the left photo ... Path #BloodSmear #Blood ... #Smear #SickleCells
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... non-specific red cell ... polychromatophilic cells ... hemolytic #anemia #Hematology ... #Pathology #Smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
..A peripheral-blood ... smear showed numerous ... resolve despite blood ... #NEJM #clinical ... #smear