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anemia management leukemia causes chronic cll hemolytic lymphocytic agglutinin algorithm aplastic autoinflammatory babesia babesiosis bloodsmear classification coagulation cold dic differential
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... vasculitis • Hematologic ... including peripheral blood ... NEJM Review: https
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... and laboratory diagnosis ... polychromatophilic cells ... hemolytic #anemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... cells, red blood ... smear • Bone marrow ... #diagnosis #hematology ... #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal Blood ... Smear • Drugs ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... hemolytic- uremic syndromes ... #Clinical #Path ... #Smear #Schistocytes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... • Peripheral smear ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... Lymphocytosis: Absolute blood ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... lymphocytes, smudge cells ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... smear - RBC agglutination ... cells (RBCs) at ... hemolytic #anemia #hematology
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