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diagnosis anemia leukemia agglutinin algorithm causes chronic classification cll cold disease elevatedmcv hemolytic hodgkins lymphoma macrocytic macrocytosis management mds myelodysplasia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Peripheral smear ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... • Peripheral smear ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... count with differential ... smear • Bone marrow ... #diagnosis #hematology ... #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Algorithm Normal Blood ... Smear • Drugs ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... Immunohistochemical studies (to differentiate ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... smear - RBC agglutination ... younger pts) Differential ... cells (RBCs) at ... hemolytic #anemia #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... pulses, bruits, or blood ... Multinucleated giant cells ... elevated protein, lymphocytic ... #Diagnosis #Rheumatology
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