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diagnosis leukemia anemia chronic cll mds myelodysplastic algorithm aplastic autoinflammatory causes classification differential e1 elevatedmcv hemeonc hodgkins lymphoma macrocytic macrocytosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... cells, red blood ... cells - red blood ... smear • Bone marrow ... #hematology #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... multiple myeloma, myelodysplastic ... multiple myeloma or myelodysplastic ... including peripheral blood ... NEJM Review: https
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... , smudge cells are ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... = funny-shaped cells ... #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Peripheral smear ... Lymphocytosis: Absolute blood ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... • Peripheral smear ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Algorithm Normal Blood ... Smear • Drugs ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... Algorithm #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• Hypocellular myelodysplastic ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
HL (MCHL) - Lymphocyte ... Workup: • Full Blood ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
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