15 results
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
eosinophils may also ... of inflammatory cells ... • ANS activation ... #Anaphylaxis #pathophysiology ... #immunology
A Lewis Lead (also called the S5 lead) is a modified ECG lead used to detect
A Lewis Lead (also ... is a modified ECG ... clinically, based on signs ... I on the ECG and ... #Cardiology #EKG
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... Inability to produce all ... humoral immunity Signs ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
such as peptides ... Ags tagged with ... storage sites (e.g ... Humoral #Immunity #pathophysiology ... #immunology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
excess secretion of hCG ... pituitary can also ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
exposed tothe sun (e.g ... same precursor as ... abdominal CT, pelvis ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension is defined as ... hypertension and signs ... renal bruit or signs ... Vasculitis • Endocrinologic ... Hypercalcemia, Cushing's
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
14 surge in LH also ... follicle's granulosa cells ... implantation does occur, HCG ... #OvarianCycle #pathophysiology ... #LutealPhase #endocrinology