39 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... mutated in all cells ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... an involuntary reflex ... #Meningitis #Clinical ... #Video #PhysicalExam
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
such as reflex ... further guide management ... orthostatic vital sign ... Further diagnostics ... should be guided by clinical
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... - Erosions and crusts ... #Management #dermatology
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
the long bone or pelvis ... accounts for —9096 of cases ... Pathophysiology ... FES is a clinical ... #Signs #Symptoms
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
skin syndrome, caused ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... • Examine for signs ... Casey Albin MD @ ... caseyalbin #PhysicalExam
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... - Causes progressive ... Increased Jaw Jerk reflex ... #management