8 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Allergic reaction ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
and induce mast cell ... plasma cells that ... complexes bind to mast cells ... • Inflammatory cells ... #Immunology #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
surfaces of body cells ... -> B-Cells with ... foreign -> B-cells ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
maturation of B cells ... from precursor cells ... Absence of mature B cells ... CD19+) and plasma cells ... #immunology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... are the immune cells ... between nerve cells ... Lateral #Sclerosis #neurology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Gitelman SIGNS ... smooth muscle cells ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... Pleocytosis > 100 cells ... diagnosis #management #neurology