13 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... and Aldosterone Receptor ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Basiliximab - IL-2 receptor ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... imports K+ into cells ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin II Receptor ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... Lipolysis #Adrenoceptor ... #adrenergic #receptors ... #actions #pharmacology ... #pathophysiology
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... to the B-cell receptor ... to the T-cell receptor ... ImmuneResponses #immunology ... #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... Thrombocytosis: cells ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Antigen binds receptor ... foreign -> B-cells ... the cell surface receptor ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... These T cells then ... binds the FceRI receptor ... #asthma #pathophysiology ... #inflammatory #immunology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
binds to androgen receptor ... LUTS - LHRH receptor ... testicular Leydig cells ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology