14 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... of UMN and LMN signs ... and with limb features ... by decreasing activity
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... worrisome EKG features
Pathogenesis of meningitis 

Risk factors for pathogen entry include immunocompromised state (HIV positive, cancer, chemotherapy patients,
which produces the complications ... and clinical features ... damages pathogens as ... well as the nearby ... #Meningitis #Pathophysiology
Non-Infective Endocarditis (NBTE / Marantic Endocarditis)
Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
endocarditis is also ... Inflammatory cells ... pathognomonic signs ... symptoms or echo features ... Marantic #diagnosis #pathophysiology
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
/ Behavioural Features ... Problems and Facial Features ... Symptoms related to complications ... , such as frequent ... BulimiaNervosa #pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Joint diseases features ... • Plasma cells ... reactants are also ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Diagnosis and Clinical Features ... same precursor as ... , pathological fractures ... mineralocorticoid activity ... Hypercortisolism #Diagnosis #signs
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... Langerhans giant cells ... characteristic features ... • GU system Complications
Pediatric Trauma Primary Survey: C-ABCDE
C - Catastrophic Bleeding - Life-threatening hemorrhage
 • Apply direct pressure/compression bandage
Pediatric Trauma ... potential pelvic fracture ... • If active bleeding ... need For blood, activate ... cord injury #Pediatrics