5 results
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
=> Immediate Phase ... Lipid mediators (e.g ... of inflammatory cells ... #pathophysiology ... #immunology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... inotropy) ACCP Cardiology ... Antiarrhythmics #Pharmacology ... #pathophysiology ... #phases #cardiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
++ influx into cells ... inotropy) ACCP Cardiology ... Vaughan #Williams #Pharmacology ... #pathophysiology ... #cardiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
countries (11-24 cases ... Americans (18-71 cases ... mortality: 9-14 cases ... sarcoidosis (1/3 of cases ... sarcoidosis (2/3 of cases
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
positive in 90% of IE cases ... • Petechiae Immunologic ... Cholesterol emboli syndrome ... ↑ ESR, CRP • EKG ... Differential #Diagnosis #cardiology