22 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... pattern of spread, B symptoms ... Responsive to Treatment ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
In order to better classify heart failure, the American College of Cardiology Foundation and the American
American College of Cardiology ... based solely on symptoms ... With treatment, ... patients with a diagnosis ... #Diagnosis #Cardiology
Traditionally, congestive heart failure has been classified according to severity of symptoms, first formulated by the
to severity of symptoms ... sometimes advanced treatment ... III and class IV symptoms ... #Diagnosis #Cardiology ... HeartFailure #Staging #Classification
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... Syndrome #TLS #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
natural killer cells ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Reactions #hematology #diagnosis ... #comparison #table
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... ++ influx into cells ... Vaughan #Williams #Pharmacology ... #Classes #pathophysiology ... #cardiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... and iron release Diagnosis ... functional ID) Treatment ... improvement in symptoms ... #management #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... inotropy) ACCP Cardiology ... #Classification ... #Classes #pathophysiology ... #phases #cardiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... : >3 symptoms, or ... Renal Failure Treatment