13 results
Major Chemotherapy Toxicities - AntiNEOPlastic Man Mnemonic

Common Toxicities with Traditional Chemotherapeutic Medications 

Originally posted on pharmacologyweekly
Toxicity #Toxicities #SideEffects ... #Adverse #Pharmacology ... AntiNeoplastic #Man #Oncology ... #Table
Adverse Effects of Antipsychotic Medications - Comparison Table

First Generation: chlopromazine, haloperidol, fluphenazine 
Second Generation: aripirazole, asenapine,
Medications - Comparison Table ... Dyslipidemia, Weight Gain ... Antipsychotics #SideEffects ... Adverse #Psychiatry #Pharmacology ... Profiles #Comparison #Table
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... New-onset back pain ... Chest and shoulder pain ... Dyspnea, chest pain
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Inhibitor Toxicity Main ... Toxicity #Toxicities #SideEffects ... #Table #Diagnosis ... #Pharmacology # ... Oncology
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
ANC <500 x 10^9 cells ... • Abdominal pain ... Diagnosis #criteria #hematology ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Alcohol-induced pain ... : Pain in involved ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Side Effects of Atypical and Typical Antipsychotics - Comparison Table
Atypical antipsychotics: Risperidone, Quetiapine, Olanzapine, Amisulpride, Ziprasidone
Antipsychotics - Comparison Table ... dyslipidaemia, weight gain ... Antipsychotics #SideEffects ... Profiles #Comparison #Table ... #Psychiatry #Pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
#Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... Headaches, bone pain ... , fever, joint pain ... #Leukemia #Hematology ... #Oncology #Diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
brain • Weight Gain ... arterioles -> less able ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology #