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hematology acidosis causes chronic classification differentiation elevation lactic leukemia lymphocytic management mds myelodysplasia myelodysplastic syndromes typea typeb workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... aplasia • ITP ... • Richter’s Syndrome ... Transform to DLBCL, PML ... #workup #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... initiation • Differential ... #APML #diagnosis ... management #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... blood count with differential ... progression to AML ... #diagnosis #hematology ... #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... the critically ill ... / hypoxemia -> focus ... - Compartment syndrome
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