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hemophagocytic lymphohistiocytosis rheumatology summary treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood cells ... Auto-amplification loop Diagnosis ... Purtilo (XLP) Acquired ... #management #treatment
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