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diagnosis hematology treatment differential idsa oncology algorithm causes hemophagocytic hivaids hlh inflammatory latenttb lymphohistiocytosis opportunistic pharmacology prevention product reactions syndrome
IDSA Recommendations for Treating Isospora belli Infection in HIV-AIDS Treating Isospora belli Infection General Management Considerations: • Fluid
Treating Isospora belli ... Treating Isospora belli ... CD4 count >200 cells ... without evidence of active ... I. belli infection
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). Mild infection: for
Algorithm for the Management ... Mild infection: ... abnormal white blood ... 12 000 or <400 cells ... SSTIs #Algorithm #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... for 4.6% of new infections ... macrophages and T cells ... Langerhans giant cells ... TB #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Activation of CD8 T cells ... Phagocytosis of blood ... cells + production ... Lymphohistiocytosis #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy • Blast cells ... Rapidly rising blast cells ... Tyrosine Kinase activity ... : Granulocytic cells ... organs When Cancer Cells
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
. tuberculosis infections ... for 4.6% of new infections ... macrophages and T cells ... Langerhans giant cells ... TB #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... History of EBV infection ... Workup: • Full Blood ... • PET scan - activity ... hematology #oncology #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... result from low blood
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Algorithm Red blood ... cells on urine ... Hematuria with active ... Hematuria with active ... glomerulonephritis • Post-Infectious
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
accumulates in cells ... Increased PKC Activity ... Decreased insulin in blood ... the decreased blood ... Osteomyelitis - Infection
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