41 results
Persistent Pupillary Membrane (PPM) on Slit Lamp Ocular Examination

This membrane would be a remainder of the
tunica vasculosa lentis ... low vision or symptoms ... PhysicalExam #clinical #video ... ophthalmology #SlitLamp
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... Diagnosis #Signs #Symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Iridodonesis

Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
sign of ectopia lentis ... Iridodonesis #Iris #SlitLamp ... #PhysicalExam #Video
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
the long bone or pelvis ... Pathophysiology ... Diagnosis #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... pattern of spread, B symptoms ... Classification #pathophysiology
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... lymphocytes and plasma cells ... ‘Leakage’ symptoms ... Endocrinology #Diagnosis #Pathophysiology
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Characterized by red blood cells ... These cells can ... The underlying pathophysiology ... sequestration of sickle cells ... Features #Signs #Symptoms