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diagnosis management rheumatology alkaline alp common cryofibrinogenemia cvid gca giantcell hepatology hyophosphatasia hypogammaglobulinemia immunodeficiency immunology low phosphatase signs sjogrens symptoms
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Secondary form associated ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... to medium-sized arteries ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
particularly those coming ... Diagnosis = clinical ... systemic complaints- anemia ... identifies 85 to 95% of cases ... them, but urgent rheumatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Adult form: Less ... pain • loss of secondary ... • Pernicious anemia ... Phosphatase: • Other causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... Arthralgia and Arthritis
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