17 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... prevalence of 1- ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Diabetes Insipidus Workup ... Step #1 - Consider ... history Step #2 ... #Algorithm #Sodium ... #nephrology #insipidus
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... #Differential #Algorithm ... Diagnosis #Causes #Workup ... #Nephrology
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
kaliuresis step 1 ... hypovolemic step 2 ... #kaliuresis #management ... diuretics #diuresis #nephrology ... #algorithm
Causes of Hypokalemia - Differential Diagnosis Algorithm
Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Differential Diagnosis Algorithm ... discrete buckets: 1. ... (low intake) 2. ... #Causes #workup ... #nephrology
Hyperkalemia management algorithm 2023-2024 based on UKKA and KDIGO guidelines.

#hyperkalemia #electrolytes #algorithm #emergency #management

Notes:

(1) Up to
Hyperkalemia management ... #management ... Notes: (1) Up ... monitored (2) ... lowering drug (sodium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... acidosis (type 1 ... of 2), Ureterosigmoidostomy ... Bartter's syndrome, Gitelman's ... #causes #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... Step 1 . ... Repeat the sodium ... Step 2. ... #Algorithm #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... renal mechanism 2) ... #Algorithm #nephrology ... #sodium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypokalemic salt-losing ... thiazide-sensitive sodium ... thiazide-sensitive sodium ... Syndrome #diagnosis #nephrology ... #management #pathophysiology