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nephrology pathophysiology syndrome differential hypokalemia alkalosis bartter hypochloremia management metabolic urinary urine
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
Gitelman syndrome ... syndrome • Urine Chloride ... • Urine Ca/Cr ... #nephrology #hypokalemia ... #diagnosis
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... thiazide-sensitive sodium-chloride ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Algorithm Cl- ... alkalosis • Normal/low ... Bartter syndrome, Gitelman ... #urine #Algorithm ... #diagnosis
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
- Differential Diagnosis ... Algorithm Cause ... Decreased Intake: • Low ... - Bartter - Gitelman ... #Nephrology #Chloride
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
hypokalemic salt-losing ... alkalosis • Normal or low ... • Congenital chloride ... #Syndrome #diagnosis ... #nephrology #management
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