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diagnosis dermatology classification causes cutaneous dermatologic granulomatosis management nonpalpable petechiae petechial physicalexam polyangiitis prs pulmonary purpura rapidly renal rpgn skin
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... MPO-ANCA (P-ANCA ... #Vasculitis #differential ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... mucositis - Rash ... (Dx: GPA, EGPA, ... Serologies for Cryoglobulins ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... triad of Palpable ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... classification #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vessel: Petechiae, Palpable ... ANCA Associated: ... - Microscopic ... - GPA Cutaneous ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... RA, Sjogren's, GPA ... , EGPA, Microscopic ... Measurement of antinuclear ... immunoglobulins & cryoglobulins
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /HSP • Cryoglobulinemia ... (MIXED) • ANCA ... #Diagnosis #hematology ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
reticularis Differential ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... , mucositis • Rash ... )): Microscopic ... + MPO) Cryoglobulinemic ... Diagnosis #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... • Cutaneous: palpable ... Auto-antibodies: ANCA ... Path: rapidly progressive
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