5 results
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Serum levels of PTH ... hypocalcemia: - Hypoparathyroidism ... - Calcium-sensing ... activating mutation - Parathyroid ... #Diagnosis #Endocrinology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: ↑→PTH, ↑Calcium ... : ↑PTH, ↓→Calcium ... : ↑↑PTH, ↑Calcium ... #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
production - Hyperparathyroidism ... Incr levels of parathyroid ... > Clearance of calcium ... Signs #Symptoms #Pathophysiology ... #Diagnosis
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... precipitates with calcium ... Imaging may show chondrocalcinosis ... Intracellular (leukocyte ... Gout #Comparison #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Disease (CPPD) Pathophysiology ... Hemochromatosis • Hyperparathyroidism ... culture used to diagnose ... Imaging may show chondrocalcinosis ... Deposition #Disease #Rheumatology