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Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... Acute transfusion reaction ... recruitment of leucocytes ... #types #allergy
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... common immune reaction ... - Allergic ... reaction: Usually ... proteins on plts, leukocytes
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... common immune reaction ... once had another reaction ... • Allergic reaction ... proteins on plts, leukocytes
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... #Allergic #Reactions
Allergic Reaction Classification
Type 1 reaction: Acute anaphylactic reaction
Type 2 reaction: Cytotoxic reaction
Type 3 reaction: Immune complex
Type
Allergic Reaction ... Type 2 reaction ... Type 3 reaction ... #Allergic #Reaction ... Classification #Types #allergy
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
A reaction to phagocytosed ... Intracellular (leukocyte ... Risk for severe allergic ... reactions • Serum
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... reaction. ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen
Drug Treatment of Anaphylaxis and Allergic Reactions
First-Line Therapy 
 - Epinephrine 
 - Oxygen 
 -
Anaphylaxis and Allergic ... Reactions First-Line ... #Medications #Allergy
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... HypersensitivityReaction #Allergy
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
reaction • Type ... reaction • Type ... reaction • Type ... An allergic reaction ... #Allergic #Reactions