11 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury ... Wilson disease ... Primary biliary cholangitis ... #Causes #Differential ... #Hepatology #Diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... • Placenta • Leukocytes ... elevation DDX of Hepatic ... Primary biliary Cholangitis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... • Hepatic vein: ... #injury #hepatitis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... #Injury #Differential ... #Diagnosis #Causes ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... disease, Hepatic ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... replaced by non-hepatic ... disease: > 2 ... #chemistry #diagnosis ... #differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... ) Pathophysiology ... acid metabolism products ... infiltration) Differential ... Hepatitis, Preeclampsia
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... and hemorrhage Acute ... #hepatitis #comparison ... #differential # ... diagnosis #icp #
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... bile ducts Differential ... Viral hepatitis, ... malignancies, Hepatic ... #hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Types: • Leukocyte ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology