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hepatology algorithm management blood alkaline alp biliary chemistry cirrhosis dili druginduced elevation fatty interpretation lfts liverinjury obgyn obstetrics pbc phosphatase
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Acute Liver Injury ... Wilson disease ... Primary biliary cholangitis ... #Causes #Differential ... #Hepatology #Diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... • Placenta • Leukocytes ... elevation DDX of Hepatic ... Primary biliary Cholangitis ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... #Injury #Differential ... #Diagnosis #Causes ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes ... of Acute Liver ... Injury: • Hepatic ... #injury #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... for alternative causes ... disease, Hepatic ... dechallenge • Acute ... #Injury #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... ) Pathophysiology ... acid metabolism products ... infiltration) Differential ... Hepatitis, Preeclampsia
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... replaced by non-hepatic ... disease: > 2 ... #chemistry #diagnosis ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... bile ducts Differential ... Viral hepatitis, ... malignancies, Hepatic
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Types: • Leukocyte ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
proteins on plts, leukocytes ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
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