7 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
• Placenta • Leukocytes ... - Drugs - Pregnancy ... elevation DDX of Hepatic ... Primary biliary Cholangitis ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Toxic: Medication, Pregnancy ... #Injury #Differential ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... melanoma, myeloma • Pregnancy ... #injury #hepatitis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... acid metabolism products ... Hepatitis, Preeclampsia ... Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Pregnancy (AFLP) ... #Disease #Pregnancy ... #differential # ... diagnosis #icp #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... replaced by non-hepatic ... disease: > 2 ... #chemistry #diagnosis ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... bile ducts Differential ... Viral hepatitis, ... cholestasis of pregnancy ... malignancies, Hepatic