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differential management neurology hematology classification guillain treatment anemia aplastic bee cns common cryofibrinogenemia cryoglobulinemia cryoglobulins cvid gbs guillainbarre hypogammaglobulinemia immunodeficiency
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... : HCV infection, ... HBV infection, ... HIV infection ... classification #rheumatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Summary Acute AIDP ... Pathophysiology: • Immune ... response preceding infection ... #Syndrome #diagnosis
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... Immune-mediated ... conjunction with symptoms ... pachymeningitis • HIV ... MRI lesions and clinical
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... than one after symptom ... #Syndrome #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... to exclude are infections ... Presentation - Systemic Symptoms ... Cryoglobulins • HIV ... #rheumatology #
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... should be based on clinical ... required until immune ... Demyelinating disease caused ... #AIDS #opportunistic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... - HIV • Immune ... CMV) • Epstein-Barr ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... (specifically immune ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Presentation: Systemic Symptoms ... • Progressive symptoms ... tract, and often causes ... #Rheumatology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... Meningitis • Include: vasculitis ... • Caused by immune ... #Tuberculosis #diagnosis
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