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diagnosis reactions activation classification hemophagocytic hlh hodgkins lymphohistiocytosis lymphoma mas oncology summary syndrome transfusion transfusions
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... Fibrin degradation products ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... cutaneous eruptions, diarrhea ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
activation of macrophages ... Phagocytosis of blood ... • Clinical: fever ... Autoimmune diseases: SLE ... #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
proteins on plts, leukocytes ... cutaneous eruptions, diarrhea ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... genes and gene products ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
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