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differential management oncology causes leukemia product reactions anemia cbc chronic classification cll dermatology erythematosus fetal hemolytic lupus lymphocytic lymphoma neutrophil
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Lymphoma Workup ... : • Full Blood ... number of sites of disease ... classification #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... vasculitis, malignant hypertension ... bartonella (oroya fever ... #Algorithm #workup ... #hematology #testing
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm Excessive Uterine Activity: • Hyperstimulation • Placental
• Respiratory disease ... Decreased Uterine Blood ... Flow: • Hypotension ... Conditions: • Fever ... #Oxygenation #Hypoxia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... manifestations, hypoxia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
leukocytes. ... • Autoimmune diseases ... tachycardia or fever ... bacteremia and hypotension ... neutrophil #WBC #CBC #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... Red Flags: • Fever ... appearance • Hypotension ... deficiency Work ... coagulation studies • Urinalysis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... cells can indicate disease ... Lymphocytosis: Absolute blood ... #workup #oncology ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... progressing to severe hypoxemia ... bleeding - Hypotension ... #Transfusions #diagnosis ... #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Differential Diagnosis ... Frank nephritis (hypertension ... • CBC, TSH and urinalysis ... cyclophosphamide) • Hodgkin
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
proteins on plts, leukocytes ... progressing to severe hypoxemia ... ↑bleeding • Hypotension ... #Transfusion #diagnosis ... #management #hematology
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