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oncology workup agglutinin arthritis bandemia cbc chronic cold hemolytic laboratory lupus lymphocytic mds myelodysplasia myelodysplastic neutrophil pathophysiology rheumatic rheumatoid sle
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... • Neutropenia, anemia ... aplasia • ITP ... #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... edema, active urine ... lymphopenia, low PLT • Anemia ... Hodgkin lymphoma and leukemia ... #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
syndrome (Clinical ... disease) Differential ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... • Aplastic Anemia ... Cell Leukemia ... Myeloproliferative Disease ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... passage of red-brown urine ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... leukocytes. ... Tissue damage • Leukemia ... • Autoimmune diseases ... #WBC #CBC #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... pulses, bruits, or blood ... ischemia • Skin: Erythematous ... vasculitis • Behcet ... #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... the presence of anemia ... • Serum and urine ... #testing #Rheumatology
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