16 results
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
, erythema and WBC ... effusion with few WBCs ... morning • Effusion leukocyte ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... Synovial Fluid: • WBCs ... Fluid Testing: • WBCs ... Intracellular (leukocyte ... #Comparison #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... , gout or pseudogout ... Inflammatory, crystalline disease ... Joint #Pain #MSK #rheumatology ... #approach #workup
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... Must rule out other ... low ferritin, arthritis ... synovitis (40%) Treatment ... #AOSD #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... synovial fluid • Gout ... urate crystals (gout ... #laboratory #workup ... diagnosis #testing #Rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
frequent attacks • Arthritis ... Fluid Testing: • WBCs ... Intracellular (leukocyte ... treatment; consider ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... Negative, ruling out ... from ischemia WBC ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and often causes arthritis ... Glomerulonephritis, arthritis ... Vessels: Supply gut ... Lab Tests: • CBC ... differential #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... cells can indicate disease ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology