6 results
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Stabilization Concern for Liver ... GI Bleed: • Peptic ... GAVE (idiopathic, liver ... UGIB #GIBleed #Differential ... gastrointestinal #gastroenterology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... • Reduced liver ... #hematology #coagulation
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... #diagnosis #algorithm
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
• Factor VIII level ... deficiency • Liver ... suggests liver ... these causes are liver ... Acquired: • Liver
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... Petechial or purpuric rash ... thrombocytopenia • Liver ... ALT ↑ bilirubin level ... Hypofibrinogenemia • ↑ PT ↑ PTT