11 results
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
vitamin B12 serum level ... for all patients ... the most likely cause ... #Diagnosis #Macrocytosis ... #AAFP
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... Low phosphorus level ... • Pernicious anemia ... Hyophosphatasia #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... index < 2 • EPO Level ... #oncology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... #oncology #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Headaches, bone pain, fever ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... involve one, two, or all ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
the Journal of Clinical ... phlebotomy/ blood work ... reasoning during clinical ... of unnecessary diagnostic ... #differential #diagnosis
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
the Fingers Clinically ... include diabetes, anemia ... Abnormal #Pathology #Diagnosis ... #Clinical #Signs ... #PhysicalExam #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Castleman disease • AL ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... #differential #diagnosis