163 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... DILI and Type of Liver ... LiverInjury #Hepatology #Pharmacology ... #Causes #DILI
Drugs that Cause Fever
Most commonly:
Amphotericin B, Antihistamines, Asparaginase, Barbiturates, Bleomycin sulfate, Methyldopa, Penicillins, Phenytoin sodium, Procainamide,
Drugs that Cause ... Fever Most commonly ... hydrochloride #Drug #Fever ... #causes #differential ... #diagnosis #pharmacology
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Treatment of Wilson's ... Aims to reduce level ... Wilsons #Disease #Treatment ... #management #pharmacology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
production • Treatment ... rapidly fatal • Causes ... Serotonin syndrome • Treatment ... Identify underlying cause ... Cooling blankets can cause
Migraine - Preventative Treatments

 • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin
 • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
- Preventative Treatments ... Cyproheptadine * Level ... #Preventative #Treatment ... prophylaxis #prevention #pharmacology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... should be TS and SF level ... out additional causes ... evaluation for other causes ... If other causes
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... Ranges #Toxicology #Pharmacology
Liver Abscess
•	Pyogenic abscess, accounts for 80% of abscess.
•	Amebic abscess due to Entamoeba histolytica, accounts for 10%.
•	Fungal
Liver Abscess • ... the bacterial cases ... abscess & antibiotic treatment ... cornerstones of treatment ... drainage- first-line treatment
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... m2 • Severe liver ... e.g. diarrhea, nausea ... #Metformin #Pharmacology
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... indicate preferred treatment ... the perceived level