13 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... #Diagnosis #Management
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #skin #rashes #differential
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... symptomatology Differential ... Complex: Systemic lupus ... #differential # ... diagnosis #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... to: Arthritis, Fever
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Red Flags: • Fever ... Autoimmune Vasculitis (lupus ... blood test • Serology ... #Differential #
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... D-lactate (short bowel syndrome ... Anxiety, pain, fever ... Diagnosis #Summary #Nephrology ... #ABG #bloodgas
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... have drop in Hct, fever ... maculopapular rash ... Sx include: fever ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... maculopapular rash ... Sx include: fever ... #hematology #reactions
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Fever >38.5 2. ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... Coronary arteries - Fever ... mucositis - Rash ... such as systemic lupus ... Vasculitis: • Fevers