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diagnosis hematology algorithm lymphoma rash causes cell cellulitis chronic classification clinical cll comparison infection infections intermittent legs leukemia lymphocytic management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... nodosum • Immune hemolytic ... Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #oncology #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... bartonella (oroya fever ... #Anemia #Differential ... Diagnosis #Algorithm #workup
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... schistosomiasis • Pyemia ... 1-2 weeks • Hodgkin ... with profound hemolysis ... #Patterns #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... mountain spotted fever ... #nonpalpable #dermatology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
Rapid onset of fever ... hemochromatosis, hemolytic ... anemia, CKD, hiv ... immunosuppressive meds ... rash #cellulitis #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... Lymphadenopathy • Fevers ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Red Flags: • Fever ... deficiency Work ... • Abdominal ultrasound ... Algorithm #Causes #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
bone marrow at a level ... • No CRAB - no anemia ... macroglobulinemia • Non-Hodgkin ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
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